Skip to main content
 

About

The Atomic Absorption Spectrometry Lab provides analysis that is used to determine the levels of arsenate, methylated and other organic forms of arsenic in solutions and/or matrices.

Services

Oxidation state-specific analysis of arsenic (aqueous solutions or simple biological matrices)
Trivalent and pentavalent arsenic species in aqueous solutions or simple biological matrices (e.g., cell culture medium or urine) are analyzed directly (without extraction or chemical digestion) using hydride generation-cryotrapping-atomic absorption spectrometry (HG-CT-AAS). This method detects and quantifies 7 arsenic species, including arsenite, arsenate, methylarsenite, methylarsenate, dimethylarsenite, dimethylarsenate, and trimethylarsine oxide.

Oxidation state-specific speciation analysis of arsenic (aqueous solutions or simple biological matrices) with very low arsenic content
Trivalent and pentavalent arsenic species in aqueous solutions or simple biological matrices (e.g., cell culture medium or urine) are analyzed directly (without extraction or chemical digestion) using HG-CT-inductively coupled with the plasma-mass spectrometer (ICP-MS). This method can detect and quantify very low levels of 7 arsenic species, including arsenite, arsenate, methylarsenite, methylarsenate, dimethylarsenite, dimethylarsenate, and trimethylarsine oxide.

Speciation analysis of arsenic (complex biological matrices)
Arsenic species in complex biological matrices (e.g., sediments, cells or tissues) are analyzed after extraction or chemical digestion of samples using HG-CT-AAS. This method detects and quantifies inorganic arsenic, methylarsenic, dimethylarsenic and trimethylarsenic without providing information on the oxidation state of arsenic in the above species.

Speciation analysis of arsenic (aqueous solutions or simple biological matrices)
Arsenic species in aqueous solutions or simple biological matrices (e.g., cell culture medium or urine) are analyzed directly (without extraction or chemical digestion) using HG-CT-AAS. This method detects and quantifies inorganic arsenic, methylarsenic, dimethylarsenic and trimethylarsenic without providing information on the oxidation state of arsenic in the above species.

Speciation analysis of arsenic (aqueous solutions or simple biological matrices) with very low arsenic content
Arsenic species in aqueous solutions or simple biological matrices (e.g., cell culture medium or urine) are analyzed directly (without extraction or chemical digestion) using HG-CT-inductively coupled with the plasma-mass spectrometer (ICP-MS). This method can detect and quantify very low levels of inorganic arsenic, methylarsenic, dimethylarsenic and trimethylarsenic without providing information on the oxidation state of arsenic in the above species.

Contact

Mirek Styblo, PhD

Professor, Nutrition

2302 Michael Hooker Research Center
CB# 7461
Chapel Hill, NC 27599

(919) 966-5721
styblo@med.unc.edu

Director, Atomic Absorption Spectrometry Lab (Chapel Hill)